Ntng1^tm2.1Ito
Targeted Allele Detail

Summary

• Symbol: Ntng1^tm2.1Ito
• Name: netrin G1; targeted mutation 2,1 Shigeyoshi Itohara
• MGI ID: MGI:6317424
• Synonyms: netrin-G1^flox
• Gene: Ntng1 Location: Chr3:109687356-110051327 bp, - strand Genetic Position: Chr3, 48.47 cM, cytoband G1
• Alliance: Ntng1^tm2.1Ito page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:254126
• Parent Cell Line: MS12 (ES Cell)
• Strain of Origin: C57BL/6NSlc

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: LoxP sites and an FRT-flanked neomycin selection cassette were inserted to flank exon 2. The neomycin selection cassette was removed via FLP-mediated recombination. (J:254126)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ntng1 Mutation: 52 strains or lines available

References

• Original: J:254126 Zhang Q, et al., Netrin-G1 regulates fear-like and anxiety-like behaviors in dissociable neural circuits. Sci Rep. 2016 Jun 27;6:28750
• All: 2 reference(s)