Tg(Ttr-Hes6)1Ital
Transgene Detail

Summary

• Symbol: Tg(Ttr-Hes6)1Ital
• Name: transgene insertion 1, Iannis Talianidis
• MGI ID: MGI:6317407
• Transgene: Tg(Ttr-Hes6)1Ital Location: unknown
• Alliance: Tg(Ttr-Hes6)1Ital page

Transgene origin

• Strain of Origin: CBA/Ca C57BL/10

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Ttr-Hes6)1Ital expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Hes6 (MGI:1859852)

• Tg(Ttr-Hes6)1Ital expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Ttr (MGI:98865)

• Mutation details: The transgenic construct expresses flagged (Flag-Tag) mouse Hes6 under the mouse Ttr promoter. Transgene expression reaches maximum levels at P30. This transgenic line expresses Hes6 at 2-fold higher than endogenous levels. (J:156389)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:156389 Martinez-Jimenez CP, et al., Hepatocyte nuclear factor 4alpha coordinates a transcription factor network regulating hepatic fatty acid metabolism. Mol Cell Biol. 2010 Feb;30(3):565-77
• All: 1 reference(s)