Il1rapl1^tm1Mmsh
Targeted Allele Detail

Summary

• Symbol: Il1rapl1^tm1Mmsh
• Name: interleukin 1 receptor accessory protein-like 1; targeted mutation 1, Masayoshi Mishina
• MGI ID: MGI:6317399
• Gene: Il1rapl1 Location: ChrX:85784476-87159251 bp, - strand Genetic Position: ChrX, 39.89 cM
• Alliance: Il1rapl1^tm1Mmsh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:269050
• Parent Cell Line: RENKA (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 3 was replaced with a pgk-1 promoter-driven neomycin phosphotransferase gene (pgk-neo) cassette. (J:269050)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Il1rapl1 Mutation: 14 strains or lines available

References

• Original: J:269050 Yasumura M, et al., IL1RAPL1 knockout mice show spine density decrease, learning deficiency, hyperactivity and reduced anxiety-like behaviours. Sci Rep. 2014 Oct 14;4:6613
• All: 1 reference(s)