Nkx2-1^tm1Jrt
Targeted Allele Detail

Summary

• Symbol: Nkx2-1^tm1Jrt
• Name: NK2 homeobox 1; targeted mutation 1, Janet Rossant
• MGI ID: MGI:6316685
• Synonyms: Nkx2-1^mCherry
• Gene: Nkx2-1 Location: Chr12:56578741-56583570 bp, - strand Genetic Position: Chr12, 24.42 cM, cytoband C1-C3
• Alliance: Nkx2-1^tm1Jrt page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:276488
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: An IRES-mCherry construct was inserted into the gene with an frt-flanked Pgk-puro-tk selection cassette. (J:276488)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nkx2-1 Mutation: 26 strains or lines available

References

• Original: J:276488 Bilodeau M, et al., Identification of a proximal progenitor population from murine fetal lungs with clonogenic and multilineage differentiation potential. Stem Cell Reports. 2014 Oct 14;3(4):634-49
• All: 1 reference(s)