Cldn1^{tm1c(NCOM)Mfgc}
Targeted Allele Detail

Summary

• Symbol: Cldn1^{tm1c(NCOM)Mfgc}
• Name: claudin 1; targeted mutation 1c, Mammalian Functional Genomics Centre
• MGI ID: MGI:6316288
• Gene: Cldn1 Location: Chr16:26175395-26190589 bp, - strand Genetic Position: Chr16, 18.0 cM
• Alliance: Cldn1^{tm1c(NCOM)Mfgc} page
• IMPC: Cldn1 gene page

Mutation origin

• Mutant Cell Line: M00022_C_364W_C10
• Germline Transmission: Earliest citation of germline transmission: J:200814
• Parent Cell Line: C2 (Tcp) (ES Cell)
• Strain of Origin: C57BL/6N
• Project Collection: NorCOMM

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion Vector: L1L2_NTARU-2
• Mutation details: The Cldn1^{tm1a(NCOM)Mfgc} allele (MGI:5765977) was FLP excised removing the neo selection cassette and lacZ reporter leaving behind the floxed critical exon(s). See http://www.mousephenotype.org/data/genes/MGI:1276109 for more information. (J:200814)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Cldn1 Mutation: 29 strains or lines available

References

• Original: J:200814 Toronto Centre for Phenogenomics, Strains and alleles submitted by Toronto Centre for Phenogenomics (NorCOMM2, funded by Genome Canada and Ontario Genomics Institute OGI-051). MGI Direct Data Submission. 2013
• All: 1 reference(s)