C8a^{tm1c(EUCOMM)Hmgu}
Targeted Allele Detail

Summary

• Symbol: C8a^{tm1c(EUCOMM)Hmgu}
• Name: complement component 8, alpha polypeptide; targeted mutation 1c, Helmholtz Zentrum Muenchen GmbH
• MGI ID: MGI:6316240
• Gene: C8a Location: Chr4:104672876-104733595 bp, - strand Genetic Position: Chr4, 48.69 cM
• Alliance: C8a^{tm1c(EUCOMM)Hmgu} page
• IMPC: C8a gene page

Mutation origin

• Mutant Cell Line: HEPD0700_2_F01
• Germline Transmission: Earliest citation of germline transmission: J:200814
• Parent Cell Line: JM8A3.N1 (ES Cell)
• Strain of Origin: C57BL/6N-A^tm1Brd
• Project Collection: EUCOMM

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion Vector: L1L2_Bact_P
• Mutation details: The C8a^{tm1a(EUCOMM)Hmgu} allele (MGI:4881019) was FLP excised removing the neo selection cassette and lacZ reporter leaving behind the floxed critical exon(s). See http://www.mousephenotype.org/data/genes/MGI:2668347 for more information. (J:200814)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any C8a Mutation: 29 strains or lines available

References

• Original: J:200814 Toronto Centre for Phenogenomics, Strains and alleles submitted by Toronto Centre for Phenogenomics (NorCOMM2, funded by Genome Canada and Ontario Genomics Institute OGI-051). MGI Direct Data Submission. 2013
• All: 1 reference(s)