Vsir^{tm1.1(VSIR)Geno}
Targeted Allele Detail

Summary

• Symbol: Vsir^{tm1.1(VSIR)Geno}
• Name: V-set immunoregulatory receptor; targeted mutation 1.1, Genoway
• MGI ID: MGI:6315562
• Synonyms: VISTA, Vsir^{tm1.1(hVSIR)Geno}, Vsir^{tm1(huVSIR-ICP3)Geno}
• Gene: Vsir Location: Chr10:60182630-60208463 bp, + strand Genetic Position: Chr10, 30.26 cM, cytoband B3
• Alliance: Vsir^{tm1.1(VSIR)Geno} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:276209
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Inserted expressed sequence)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The chimeric allele is composed of the human extracellular and transmembrane domains, and mouse intracellular domain. Flp-mediated recombination removed the selection cassette. (J:276209)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Vsir Mutation: 26 strains or lines available

Notes

https://www.genoway.com/services/catalog/humanized-mouse/immune-checkpoints.htm

References

• Original: J:276209 Sonego F, Direct Data Submission for Genoway Humanized Immune Checkpoint (ICP) Mice. MGI Direct Data Submission. 2019
• All: 2 reference(s)