Xrn2^em2Ykan
Endonuclease-mediated Allele Detail

Summary

• Symbol: Xrn2^em2Ykan
• Name: 5'-3' exoribonuclease 2; endonuclease-mediated mutation 2, Yasufumi Kaneda
• MGI ID: MGI:6307090
• Gene: Xrn2 Location: Chr2:146854916-146919920 bp, + strand Genetic Position: Chr2, 72.63 cM, cytoband H1
• Alliance: Xrn2^em2Ykan page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting to exon 1 and 2 deleted 11.6 kb including the two coding exons. (J:269711)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Xrn2 Mutation: 56 strains or lines available

References

• Original: J:269711 Nimura K, et al., Regulation of alternative polyadenylation by Nkx2-5 and Xrn2 during mouse heart development. Elife. 2016 Jun 22;5:e16030
• All: 1 reference(s)