Tg(Rarb-lacZ)#Elw
Transgene Detail

Summary

• Symbol: Tg(Rarb-lacZ)#Elw
• Name: transgene insertion, Elwood Linney
• MGI ID: MGI:6305869
• Transgene: Tg(Rarb-lacZ)#Elw Location: unknown
• Alliance: Tg(Rarb-lacZ)#Elw page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: Three retinoic acid response elements (in reverse, reverse and forward order) from the Rarb2 promoter and a herpes simplex virus thymidine kinase (TK) minimal promoter were placed upstream of the beta-galactosidase reporter gene, and SV40 intron and poly(A) signal sequences were placed downstream. Embryos of mothers treated or not treated with RA show distinct and reproducible beta-gal activity patterns. (J:274966)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:274966 Balkan W, et al., Transgenic indicator mice for studying activated retinoic acid receptors during development. Proc Natl Acad Sci U S A. 1992 Apr 15;89(8):3347-51
• All: 1 reference(s)