Retnla^em1Lvh
Endonuclease-mediated Allele Detail

Summary

• Symbol: Retnla^em1Lvh
• Name: resistin like alpha; endonuclease-mediated mutation 1, Lora Hooper
• MGI ID: MGI:6304410
• Gene: Retnla Location: Chr16:48662972-48664824 bp, + strand Genetic Position: Chr16, 30.75 cM, cytoband B5
• Alliance: Retnla^em1Lvh page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/Cas9 genome editing is used to delete exons 1-4. Western blot analysis indicates that no protein is produced. (J:274749)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Retnla Mutation: 13 strains or lines available

References

• Original: J:274749 Harris TA, et al., Resistin-like Molecule alpha Provides Vitamin-A-Dependent Antimicrobial Protection in the Skin. Cell Host Microbe. 2019 May 3
• All: 1 reference(s)