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Tg(Tcra,Tcrb)577Biat
Transgene Detail
Summary
Symbol: Tg(Tcra,Tcrb)577Biat
Name: transgene insertion 577, Biomodels Austria
MGI ID: MGI:6304250
Synonyms: Spiky, Tcr-S
Transgene: Tg(Tcra,Tcrb)577Biat  Location: unknown  
Alliance: Tg(Tcra,Tcrb)577Biat page
Transgene
origin
Strain of Origin:  C57BL/6N
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsThis transgenic line expresses a H2-Kb-restricted mouse TCR that recognizes the immunodominant epitope s598605 of the MHV spike protein (TCR-S or Spiky). (J:259742)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:259742 Cupovic J, et al., Central Nervous System Stromal Cells Control Local CD8(+) T Cell Responses during Virus-Induced Neuroinflammation. Immunity. 2016 Mar 15;44(3):622-633
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/06/2026
MGI 6.24
The Jackson Laboratory