Casd1^{tm1c(EUCOMM)Hmgu}
Targeted Allele Detail

Summary

• Symbol: Casd1^{tm1c(EUCOMM)Hmgu}
• Name: CAS1 domain containing 1; targeted mutation 1c, Helmholtz Zentrum Muenchen GmbH
• MGI ID: MGI:6303947
• Gene: Casd1 Location: Chr6:4600911-4643355 bp, + strand Genetic Position: Chr6, 1.81 cM
• Alliance: Casd1^{tm1c(EUCOMM)Hmgu} page
• IMPC: Casd1 gene page

Mutation origin

• Mutant Cell Line: HEPD0638_5_H05
• Germline Transmission: Earliest citation of germline transmission: J:101977
• Parent Cell Line: JM8A3.N1 (ES Cell)
• Strain of Origin: C57BL/6N-A^tm1Brd
• Project Collection: EUCOMM

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion Vector: L1L2_Bact_P
• Mutation details: The L1L2_Bact_P cassette was inserted at position 4607550 of Chromosome 6 upstream of exon 2 (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. A third loxP site is inserted downstream of exon 2 at position 4608344. FLP-mediated recombination removed the FRT-flanked neo cassette leaving exon 2 floxed. (J:101977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Casd1 Mutation: 38 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 1 reference(s)