Tg(G6PD)#Srn
Transgene Detail

Summary

• Symbol: Tg(G6PD)#Srn
• Name: transgene insertion, Manuel Serrano
• MGI ID: MGI:6295451
• Synonyms: G6PD^tg, G6PD-Tg
• Transgene: Tg(G6PD)#Srn Location: unknown
• Alliance: Tg(G6PD)#Srn page

Transgene origin

• Strain of Origin: (C57BL/6J x CBA)F1

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(G6PD)#Srn expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  G6PD (2539)

  G6pd2	(MGI:105977)
  G6pdx	(MGI:105979)

  Human genomic sequence including up and downstream of the gene

• Mutation details: Human genomic DNA, containing the entire glucose-6-phosphate dehydrogenase gene plus 2.5 kb upstream and 2 kb downstream sequence, was micro-injected into pronuclei of (C57BL/6JxCBA)F1 fertilized oocytes. (J:236755)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:236755 Nobrega-Pereira S, et al., G6PD protects from oxidative damage and improves healthspan in mice. Nat Commun. 2016 Mar 15;7:10894
• All: 5 reference(s)