Tbk1^em10Lutzy
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tbk1^em10Lutzy
• Name: TANK-binding kinase 1; endonuclease-mediated mutation 10, Cathy Lutz
• MGI ID: MGI:6295418
• Gene: Tbk1 Location: Chr10:121382360-121422692 bp, - strand Genetic Position: Chr10, 69.84 cM
• Alliance: Tbk1^em10Lutzy page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/Cas9 genome editing is used to introduce a 2 bp deletion frameshift mutation in exon 6. The mutation is predicted to generate a truncated protein. (J:101977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Tbk1 Mutation: 57 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 2 reference(s)