Il15ra^em2Dvs
Endonuclease-mediated Allele Detail

Summary

• Symbol: Il15ra^em2Dvs
• Name: interleukin 15 receptor, alpha chain; endonuclease-mediated mutation 2, Dave V Serreze
• MGI ID: MGI:6295128
• Synonyms: IL15ra^ex1-6del
• Gene: Il15ra Location: Chr2:11710101-11739128 bp, + strand Genetic Position: Chr2, 8.97 cM
• Alliance: Il15ra^em2Dvs page

Mutation origin

• Strain of Origin: NOD.Cg-Prkdc^scid/J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/Cas9 genome editing is used to introduce a 24,849 bp deletion encompassing 45 bp before the start codon exon 1 through 4 bp into the intron after exon 6. The deletion should eliminate every possible isoform from the Il15ra gene. (J:101977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Il15ra Mutation: 40 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 1 reference(s)