Morn3^em1(IMPC)J
Endonuclease-mediated Allele Detail

Summary

• Symbol: Morn3^em1(IMPC)J
• Name: MORN repeat containing 3; endonuclease-mediated mutation 1, Jackson
• MGI ID: MGI:6294044
• Gene: Morn3 Location: Chr5:123173832-123185079 bp, - strand Genetic Position: Chr5, 62.73 cM, cytoband F
• Alliance: Morn3^em1(IMPC)J page
• IMPC: Morn3 gene page

Mutation origin

• Strain of Origin: C57BL/6NJ
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences AAAACCTTACAGCTTCAAGG and TTCAGGGCAGAGATTCCCCG, which resulted in a 458 bp deletion beginning at Chromosome 5 position 123,040,862 bp and ending after 123,041,319 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000649828 (exon 2) and 300 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 49 and early truncation 14 amino acids later. (J:188991)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Morn3 Mutation: 39 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 2 reference(s)