Nlrp3^em1Yhsh
Endonuclease-mediated Allele Detail

Summary

• Symbol: Nlrp3^em1Yhsh
• Name: NLR family, pyrin domain containing 3; endonuclease-mediated mutation 1, Yonghong Shi
• MGI ID: MGI:6287670
• Gene: Nlrp3 Location: Chr11:59432395-59457781 bp, + strand Genetic Position: Chr11, 37.73 cM, cytoband B1.3
• Alliance: Nlrp3^em1Yhsh page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Not Specified
• TALEN technology generated a knockout allele. No information is provided. (J:273237)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nlrp3 Mutation: 69 strains or lines available

References

• Original: J:273237 Wu M, et al., NLRP3 deficiency ameliorates renal inflammation and fibrosis in diabetic mice. Mol Cell Endocrinol. 2018 Dec 15;478:115-125
• All: 2 reference(s)