Rel^coby
Chemically induced Allele Detail

Summary

• Symbol: Rel^coby
• Name: Rel proto-oncogene, NFKB subunit; coby
• MGI ID: MGI:6287253
• Synonyms: Rel^C307X
• Gene: Rel Location: Chr11:23686847-23720969 bp, - strand Genetic Position: Chr11, 14.36 cM
• Alliance: Rel^coby page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced an A to T mutation and results in the amino acid substitution of a stop codon for cysteine at position 307 (C307X). (J:272971)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rel Mutation: 47 strains or lines available

References

• Original: J:272971 Mancini M, et al., Rel-Dependent Immune and Central Nervous System Mechanisms Control Viral Replication and Inflammation during Mouse Herpes Simplex Encephalitis. J Immunol. 2019 Mar 1;202(5):1479-1493
• All: 2 reference(s)