Tg(Scgb1a1-CCL24)hE2Jlee
Transgene Detail

Summary

• Symbol: Tg(Scgb1a1-CCL24)hE2Jlee
• Name: transgene insertion hE2, James J Lee
• MGI ID: MGI:6286211
• Synonyms: Tg(Scgb1a-hCCL24)hE2JLee
• Transgene: Tg(Scgb1a1-CCL24)hE2Jlee Location: unknown
• Alliance: Tg(Scgb1a1-CCL24)hE2Jlee page

Transgene origin

• Strain of Origin: (CBA/CaJ X C57BL/6J)F1 x C57BL/6J

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(Scgb1a1-CCL24)hE2Jlee expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  CCL24 (6369)

  Ccl24

  (MGI:1928953)

• Mutation details: The rat promoter drives lung epithelium-specific expression of the human CCL24 open reading frame following by a 2.1 kb fragment of human growth hormone to provide the polyadenylation sequence. Line hE2 was generated. (J:148584)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:148584 Ochkur SI, et al., Coexpression of IL-5 and eotaxin-2 in mice creates an eosinophil-dependent model of respiratory inflammation with characteristics of severe asthma. J Immunol. 2007 Jun 15;178(12):7879-89
• All: 5 reference(s)