Ndnftm1.1(cre)Rudy
Targeted Allele Detail
|
Symbol: |
Ndnftm1.1(cre)Rudy |
Name: |
neuron-derived neurotrophic factor; targeted mutation 1.1, Bernardo Rudy |
MGI ID: |
MGI:6284835 |
Synonyms: |
NDNF-Cre, NDNF-ires-Cre |
Gene: |
Ndnf Location: Chr6:65648595-65689307 bp, + strand Genetic Position: Chr6, 30.29 cM
|
Alliance: |
Ndnftm1.1(cre)Rudy page
|
|
Germline Transmission: |
Earliest citation of germline transmission:
J:269094
|
Parent Cell Line: |
Bruce 4 (ES Cell)
|
Strain of Origin: |
B6.Cg-Thy1a
|
|
Allele Type: |
|
Targeted (Recombinase) |
Mutation: |
|
Insertion
|
|
|
Ndnftm1.1(cre)Rudy expression driven by
1 gene
Knock-in expression driven by:
|
|
|
Mutation details: The targeting vector contained, from 5' to 3', an internal ribosome entry site sequence (IRES; allows translation initiation in the middle of an mRNA sequence), the Cre recombinase sequence, a bovine growth hormone polyA sequence and a frt-flanked PGK-Neo-bGHpA cassette. Chimeric mice were bred to FLPe mice for germline removal of the PGK-Neo-bGHpA cassette.
(J:269094)
|
|
|
Activity: |
Tissue activity of this recombinase allele
|
Driver:
|
Ndnf
(mouse)
|
|
|
|
|
Original: |
J:269094 Schuman B, et al., Four Unique Interneuron Populations Reside in Neocortical Layer 1. J Neurosci. 2019 Jan 2;39(1):125-139 |
All: |
2 reference(s) |
|