Grin2b^em5Lutzy
Endonuclease-mediated Allele Detail

Summary

• Symbol: Grin2b^em5Lutzy
• Name: glutamate receptor, ionotropic, NMDA2B (epsilon 2); endonuclease-mediated mutation 5, Cathy Lutz
• MGI ID: MGI:6283621
• Gene: Grin2b Location: Chr6:135690231-136150509 bp, - strand Genetic Position: Chr6, 66.38 cM
• Alliance: Grin2b^em5Lutzy page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: CRISPR/Cas9 genome editing is used to insert loxP sequences flanking the second coding exon of Grin2b (exon 4 of Ensembl Grin2b transcript 201/ exon 5 of Ensembl transcript 202). (J:101977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Grin2b Mutation: 96 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 2 reference(s)