Prorp^{em1(IMPC)Wtsi}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Prorp^{em1(IMPC)Wtsi}
• Name: protein only RNase P catalytic subunit; endonuclease-mediated mutation 1, Wellcome Trust Sanger Institute
• MGI ID: MGI:6281941
• Gene: Prorp Location: Chr12:55349422-55429276 bp, + strand Genetic Position: Chr12, 23.91 cM, cytoband C1
• Alliance: Prorp^{em1(IMPC)Wtsi} page
• IMPC: Prorp gene page

Mutation origin

• Strain of Origin: C57BL/6N
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at Wellcome Sanger Institute using Cas9 and guides with spacer sequences AACGTTACAAGAGACTTGCA, ACTCAAGAGAGAGGATCTCT, ATAGTTAAACTAGCAGTGGA, and TACTGATAGATGATATCTTC that targeted exon(s) ENSMUSE00000307390.4 ENSMUSE00001317219.2. This resulted in deletion(s) of 511 bp (location: Chr12:55355283-55355793; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Prorp Mutation: 48 strains or lines available

References

• Original: J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023
• All: 2 reference(s)