Tg(tetO-Bcl2,-tdTomato)LM1Ryu
Transgene Detail

Summary

• Symbol: Tg(tetO-Bcl2,-tdTomato)LM1Ryu
• Name: transgene insertion LM1, Ron Yu
• MGI ID: MGI:6281738
• Synonyms: tetO-Bcl2-IRES-TdTomato
• Transgene: Tg(tetO-Bcl2,-tdTomato)LM1Ryu Location: unknown
• Alliance: Tg(tetO-Bcl2,-tdTomato)LM1Ryu page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inducible, Inserted expressed sequence, Reporter)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Tg(tetO-Bcl2,-tdTomato)LM1Ryu expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Bcl2 (MGI:88138)	encodes the Bcl2 long isoform

• Mutation details: The transgenic construct contains (from 5' to 3') the Tet response element (TRE; ~600 bp sequence composed of direct repeats of the tet operator sequence [tetO] and minimal cytomegalovirus promoter sequence [Pmin]), a ~700 bp cDNA segment encoding the long isoform of the B cell leukemia/lymphoma 2 gene, an internal ribosome entry site, a tdTomato fluorescent protein and an SV40 polyA sequence. (J:271395)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:271395 Wu Y, et al., A Population of Navigator Neurons Is Essential for Olfactory Map Formation during the Critical Period. Neuron. 2018 Dec 5;100(5):1066-1082.e6
• All: 1 reference(s)