Prelid1^em1Hfl
Endonuclease-mediated Allele Detail

Summary

• Symbol: Prelid1^em1Hfl
• Name: PRELI domain containing 1; endonuclease-mediated mutation 1, Haifan Lin
• MGI ID: MGI:6281602
• Synonyms: Prelid1^pA
• Gene: Prelid1 Location: Chr13:55469868-55473085 bp, + strand Genetic Position: Chr13, 29.8 cM, cytoband B2
• Alliance: Prelid1^em1Hfl page

Mutation origin

• Strain of Origin: (C57BL/6 x SJL)F2

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutation: Insertion
• Mutation details: CRISPR-targeting introduced a polyadenylation sequence into the 3' UTR, which prevents expression of endogenous retrotransposon sequences. (J:255070)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prelid1 Mutation: 17 strains or lines available

References

• Original: J:255070 Watanabe T, et al., Retrotransposons and pseudogenes regulate mRNAs and lncRNAs via the piRNA pathway in the germline. Genome Res. 2015 Mar;25(3):368-80
• All: 1 reference(s)