Ctcf^tm1.1Gal
Targeted Allele Detail

Summary

• Symbol: Ctcf^tm1.1Gal
• Name: CCCTC-binding factor; targeted mutation 1.1, Niels Galjart
• MGI ID: MGI:6281589
• Synonyms: Ctcf^gfp
• Gene: Ctcf Location: Chr8:106363200-106409554 bp, + strand Genetic Position: Chr8, 53.04 cM
• Alliance: Ctcf^tm1.1Gal page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:269332
• Parent Cell Line: IB10/E14IB10 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Intragenic deletion
• Mutation details: A GFP reporter gene and floxed neomycin resistance cassette replaced exons 1 and 2. Cre-mediated recombination removed the selection cassette. (J:269332)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ctcf Mutation: 78 strains or lines available

References

• Original: J:269332 Sleutels F, et al., The male germ cell gene regulator CTCFL is functionally different from CTCF and binds CTCF-like consensus sites in a nucleosome composition-dependent manner. Epigenetics Chromatin. 2012 Jun 18;5(1):8
• All: 1 reference(s)