Kctd13^tm1.1Nk
Targeted Allele Detail

Summary

• Symbol: Kctd13^tm1.1Nk
• Name: potassium channel tetramerisation domain containing 13; targeted mutation 1.1, Nicholas Katsanis
• MGI ID: MGI:6281587
• Gene: Kctd13 Location: Chr7:126528051-126544781 bp, + strand Genetic Position: Chr7, 69.25 cM
• Alliance: Kctd13^tm1.1Nk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:270354
• Parent Cell Line: G4 (ES Cell)
• Strain of Origin: (129S6/SvEvTac x C57BL/6NCrl)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 2. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 2. Cre-mediated recombination removed exon 2 and the selection cassette. (J:270354)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kctd13 Mutation: 13 strains or lines available

References

• Original: J:270354 Arbogast T, et al., Kctd13-deficient mice display short-term memory impairment and sex-dependent genetic interactions. Hum Mol Genet. 2018 Dec 26
• All: 2 reference(s)