Igf2bp2^tm1Mini
Targeted Allele Detail

Summary

• Symbol: Igf2bp2^tm1Mini
• Name: insulin-like growth factor 2 mRNA binding protein 2; targeted mutation 1, Liliana Minichiello
• MGI ID: MGI:6281580
• Synonyms: Imp2-lacZ-ko
• Gene: Igf2bp2 Location: Chr16:21877759-21982049 bp, - strand Genetic Position: Chr16, 13.02 cM
• Alliance: Igf2bp2^tm1Mini page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:271356
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• An IRES, lacZ reporter gene and floxed neomycin resistance cassette was inserted into exon 2. (J:271356)

Expression

In Mice Carrying this Mutation:	35 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Igf2bp2 Mutation: 89 strains or lines available

References

• Original: J:271356 Dai N, et al., IGF2BP2/IMP2-Deficient mice resist obesity through enhanced translation of Ucp1 mRNA and Other mRNAs encoding mitochondrial proteins. Cell Metab. 2015 Apr 7;21(4):609-21
• All: 3 reference(s)