Pirnac1^em1Arte
Endonuclease-mediated Allele Detail

Summary

• Symbol: Pirnac1^em1Arte
• Name: piRNA cluster 1; endonuclease-mediated mutation 1, TaconicArtemis
• MGI ID: MGI:6281572
• Synonyms: Del(17)4Arte, pi-Chr17-^deltaMyb
• Gene: Pirnac1 Location: unknown Genetic Position: Chr17, Syntenic

Mutation origin

• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intergenic deletion
• Mutation details: CRISPR-targeting removed 228 bp on chr17:27425220-27504428 (mm9 mouse genome assembly), containing the A-Myb transcription factor binding site that drives expression of a piRNA cluster. (J:271389)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pirnac1 Mutation: 1 strain or line available

References

• Original: J:271389 Homolka D, et al., PIWI Slicing and RNA Elements in Precursors Instruct Directional Primary piRNA Biogenesis. Cell Rep. 2015 Jul 21;12(3):418-28
• All: 1 reference(s)