Gpr183^tm1.2Flv
Targeted Allele Detail

Summary

• Symbol: Gpr183^tm1.2Flv
• Name: G protein-coupled receptor 183; targeted mutation 1.2, Richard A Flavell
• MGI ID: MGI:6281374
• Gene: Gpr183 Location: Chr14:122189963-122202607 bp, - strand Genetic Position: Chr14, 65.86 cM
• Alliance: Gpr183^tm1.2Flv page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:271341
• Parent Cell Line: JM8 (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Cre-mediated recombination removed the floxed exon 4 and the FRT-flanked neomycin resistance cassette. (J:271341)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gpr183 Mutation: 27 strains or lines available

References

• Original: J:271341 Emgard J, et al., Oxysterol Sensing through the Receptor GPR183 Promotes the Lymphoid-Tissue-Inducing Function of Innate Lymphoid Cells and Colonic Inflammation. Immunity. 2018 Jan 16;48(1):120-132.e8
• All: 2 reference(s)