Msrb2^{em1(IMPC)Wtsi}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Msrb2^{em1(IMPC)Wtsi}
• Name: methionine sulfoxide reductase B2; endonuclease-mediated mutation 1, Wellcome Trust Sanger Institute
• MGI ID: MGI:6281101
• Gene: Msrb2 Location: Chr2:19376251-19399787 bp, + strand Genetic Position: Chr2, 13.26 cM, cytoband A2
• Alliance: Msrb2^{em1(IMPC)Wtsi} page
• IMPC: Msrb2 gene page

Mutation origin

• Strain of Origin: C57BL/6N
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at Wellcome Sanger Institute using Cas9 and guides with spacer sequences AGTGCACGTGTGAGCGTCGT, CACTCTTCACGGGGAGCGGG, GCCACCAGCAGTCTCTGTAC, and TCTTGCTAATGAAACGGGTG that targeted exon(s) ENSMUSE00001237823.2. This resulted in deletion(s) of 5 bp (location: Chr2:19383193-19383197; GRCm39), 342 bp (location: Chr2:19382807-19383148; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Msrb2 Mutation: 16 strains or lines available

References

• Original: J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023
• All: 2 reference(s)