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Tg(Clec4g-icre)1.1Sgoe
Transgene Detail
Summary
Symbol: Tg(Clec4g-icre)1.1Sgoe
Name: transgene insertion 1.1, Sergij Goerdt
MGI ID: MGI:6280453
Synonyms: Clec4g-Cre, Tg(Clec4g-cre)1.1
Transgene: Tg(Clec4g-icre)1.1Sgoe  Location: unknown  
Alliance: Tg(Clec4g-icre)1.1Sgoe page
Transgene
origin
Strain of Origin:  C57BL/6NCrl
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Clec4g-icre)1.1Sgoe expression driven by 1 gene
 
Mutation detailsA cDNA containing a codon improved version of cre recombinase followed by polyA signal sequence was fused in frame into a BAC clone (RPCI-23-239-A7) at exon 1 of mouse Clec4g so that cre expression is driven by the regulatory sequences of the BAC gene. The resulting modified BAC was used to generate this transgene. Three founder lines 1.1, 1.2 and 1.3 were identified. (J:271085)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Clec4g (mouse)
Summary of all recombinase alleles driven by Clec4g.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:271085 Wohlfeil SA, et al., Hepatic Endothelial Notch Activation Protects against Liver Metastasis by Regulating Endothelial-Tumor Cell Adhesion Independent of Angiocrine Signaling. Cancer Res. 2019 Feb 1;79(3):598-610
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
07/05/2024
MGI 6.24
The Jackson Laboratory