Fgf21^em1Nju
Endonuclease-mediated Allele Detail

Summary

• Symbol: Fgf21^em1Nju
• Name: fibroblast growth factor 21; endonuclease-mediated mutation 1, Model Animal Research Center of Nanjing University
• MGI ID: MGI:6280435
• Gene: Fgf21 Location: Chr7:45263314-45264914 bp, - strand Genetic Position: Chr7, 29.38 cM, cytoband B2
• Alliance: Fgf21^em1Nju page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Not Specified
• Mutation details: CRSIPR/Cas9 technology was used to generate a knock out mouse but further information is not provided. (J:271087)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fgf21 Mutation: 24 strains or lines available

References

• Original: J:271087 Fu T, et al., Mitophagy Directs Muscle-Adipose Crosstalk to Alleviate Dietary Obesity. Cell Rep. 2018 May 1;23(5):1357-1372
• All: 1 reference(s)