Tnf^tm1(TNF)Irga
Targeted Allele Detail

Summary

• Symbol: Tnf^tm1(TNF)Irga
• Name: tumor necrosis factor; targeted mutation 1, Irenen Garcia
• MGI ID: MGI:6276665
• Synonyms: huTNF KI
• Gene: Tnf Location: Chr17:35418357-35420983 bp, - strand Genetic Position: Chr17, 18.59 cM
• Alliance: Tnf^tm1(TNF)Irga page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:270347
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Inserted expressed sequence)
• Mutation: Insertion
• The mouse gene was replaced with the human sequence. (J:270347)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tnf Mutation: 48 strains or lines available

References

• Original: J:270347 Olleros ML, et al., Control of Mycobacterial Infections in Mice Expressing Human Tumor Necrosis Factor (TNF) but Not Mouse TNF. Infect Immun. 2015 Sep;83(9):3612-23
• All: 3 reference(s)