Mab21l2^em1Kglc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Mab21l2^em1Kglc
• Name: mab-21-like 2; endonuclease-mediated mutation 1, King L Chow
• MGI ID: MGI:6276612
• Synonyms: Mab21l2(R51C)
• Gene: Mab21l2 Location: Chr3:86453357-86455590 bp, - strand Genetic Position: Chr3, 37.86 cM
• Alliance: Mab21l2^em1Kglc page

Mutation origin

• Strain of Origin: (CBA x C57BL/6)F1

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutation: Nucleotide substitutions
• Mutation details: CRISPR-targeting introduced nucleotide substitutions that result in the amino acid substitution of cysteine for arginine at position 51 (R51C). (J:269727)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mab21l2 Mutation: 22 strains or lines available

References

• Original: J:269727 Tsang SW, et al., Generation and characterization of pathogenic Mab21l2(R51C) mouse model. Genesis. 2018 Dec;56(11-12):e23261
• All: 1 reference(s)