Robo4^tm1Okada
Targeted Allele Detail

Summary

• Symbol: Robo4^tm1Okada
• Name: roundabout guidance receptor 4; targeted mutation 1, Yoshiaki Okada
• MGI ID: MGI:6276308
• Gene: Robo4 Location: Chr9:37313198-37325319 bp, + strand Genetic Position: Chr9, 20.76 cM
• Alliance: Robo4^tm1Okada page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:269279
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site and an FRT flanked inverted pgk-neo cassette replaced a genomic region including exons 2 and 3 via homologous recombination. (J:269279)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Robo4 Mutation: 91 strains or lines available

References

• Original: J:269279 Shirakura K, et al., The Robo4-TRAF7 complex suppresses endothelial hyperpermeability in inflammation. J Cell Sci. 2019 Jan 2;132(1):jcs220228
• All: 2 reference(s)