Ormdl3^tm1.1Mrl
Targeted Allele Detail

Summary

• Symbol: Ormdl3^tm1.1Mrl
• Name: ORM1-like 3 (S. cerevisiae); targeted mutation 1.1, Merck Research Labs
• MGI ID: MGI:6276290
• Gene: Ormdl3 Location: Chr11:98472120-98478071 bp, - strand Genetic Position: Chr11, 62.07 cM
• Alliance: Ormdl3^tm1.1Mrl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:269933
• Parent Cell Line: ART B6 3.6 (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exons 2 and 4 were floxed. Flp-mediated recombination removed the FRT-flanked neomycin resistance cassette. (J:269933)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ormdl3 Mutation: 8 strains or lines available

References

• Original: J:269933 Aden K, et al., ATG16L1 orchestrates interleukin-22 signaling in the intestinal epithelium via cGAS-STING. J Exp Med. 2018 Nov 5;215(11):2868-2886
• All: 2 reference(s)