Amotl1^em2Rstot
Endonuclease-mediated Allele Detail

Summary

• Symbol: Amotl1^em2Rstot
• Name: angiomotin-like 1; endonuclease-mediated mutation 2, Rolf Stottmann
• MGI ID: MGI:6276196
• Synonyms: Amotl1^D1
• Gene: Amotl1 Location: Chr9:14453262-14556352 bp, - strand Genetic Position: Chr9, 4.12 cM, cytoband A3
• Alliance: Amotl1^em2Rstot page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: A one base pair deletion was introduced by CRIPSR mutagenesis; deletion of the last T residue in codon 155 resulted in a missense and shift in the reading frame resulting in a premature stop codon. (J:270029)

Expression

In Mice Carrying this Mutation:

2 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Amotl1 Mutation: 56 strains or lines available

References

• Original: J:270029 Liegel RP, et al., Using human sequencing to guide craniofacial research. Genesis. 2019 Jan;57(1):e23259
• All: 1 reference(s)