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Endonuclease-mediated Allele Detail
Symbol: Ccdc107em1(IMPC)J
Name: coiled-coil domain containing 107; endonuclease-mediated mutation 1, Jackson
MGI ID: MGI:6275206
Gene: Ccdc107  Location: Chr4:43493365-43495921 bp, + strand  Genetic Position: Chr4, 23.04 cM
Alliance: Ccdc107em1(IMPC)J page
IMPC: Ccdc107 gene page
Strain of Origin:  C57BL/6NJ
Project Collection: IMPC
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
Mutation detailsThis allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences GGAATGTGAAACTCTCCAGT and CGGTAGCCTCAGAAACACAA, which resulted in a 1098 bp deletion beginning at Chromosome 4 position 43,494,976 bp and ending after 43,496,073 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001230953, ENSMUSE00000179397, ENSMUSE00000179398, and ENSMUSE00000179395 (exons 3-6) and 608 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 86 and early truncation 56 amino acids later. (J:188991)
Inheritance:    Not Specified
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Ccdc107 Mutation:  10 strains or lines available
Original:  J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.22
The Jackson Laboratory