Lpcat3^tm1.1Tksh
Targeted Allele Detail

Summary

• Symbol: Lpcat3^tm1.1Tksh
• Name: lysophosphatidylcholine acyltransferase 3; targeted mutation 1.1, Takao Shimizu
• MGI ID: MGI:6274935
• Gene: Lpcat3 Location: Chr6:124639887-124681142 bp, + strand Genetic Position: Chr6, 59.17 cM
• Alliance: Lpcat3^tm1.1Tksh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:229247
• Parent Cell Line: B6-3i/HK3i (ES Cell)
• Strain of Origin: C57BL/6NJcl

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 10-12 were deleted by cre-mediated recombination of flanking loxP sites. Western blot analysis of proteins from small intestine showed that no detectable protein product was expressed from this allele. (J:229247)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lpcat3 Mutation: 24 strains or lines available

References

• Original: J:229247 Hashidate-Yoshida T, et al., Fatty acid remodeling by LPCAT3 enriches arachidonate in phospholipid membranes and regulates triglyceride transport. Elife. 2015;4
• All: 1 reference(s)