Mafb^tm2.1Mhs
Targeted Allele Detail

Summary

• Symbol: Mafb^tm2.1Mhs
• Name: MAF bZIP transcription factor B; targeted mutation 2.1, Michael H Sieweke
• MGI ID: MGI:6274697
• Synonyms: MafB^flox
• Gene: Mafb Location: Chr2:160205623-160208985 bp, - strand Genetic Position: Chr2, 80.92 cM
• Alliance: Mafb^tm2.1Mhs page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:269568
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The coding region was floxed. Flp-mediated recombination removed the FRT-flanked neomycin resistance cassette inserted downstream of the coding region. (J:269568)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mafb Mutation: 22 strains or lines available

References

• Original: J:269568 Matcovitch-Natan O, et al., Microglia development follows a stepwise program to regulate brain homeostasis. Science. 2016 Aug 19;353(6301):aad8670
• All: 1 reference(s)