Pole3^em1(IMPC)J
Endonuclease-mediated Allele Detail

Summary

• Symbol: Pole3^em1(IMPC)J
• Name: polymerase (DNA directed), epsilon 3 (p17 subunit); endonuclease-mediated mutation 1, Jackson
• MGI ID: MGI:6273618
• Gene: Pole3 Location: Chr4:62440889-62443305 bp, - strand Genetic Position: Chr4, 33.17 cM, cytoband C1
• Alliance: Pole3^em1(IMPC)J page
• IMPC: Pole3 gene page

Mutation origin

• Strain of Origin: C57BL/6NJ
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at The Jackson Laboratory using Cas9 and guides with spacer sequences CATACAATGTGCTTTTGCAA and CCACTCTGACAGCTTCTGAA that targeted exon(s) ENSMUSE00001250923.2 ENSMUSE00001277871.2. This resulted in deletion(s) of 1834 bp (location: Chr4:62440864-62442697; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Pole3 Mutation: 18 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 4 reference(s)