Dnase1l3^tm1Tac
Targeted Allele Detail

Summary

• Symbol: Dnase1l3^tm1Tac
• Name: deoxyribonuclease 1-like 3; targeted mutation 1, Taconic
• MGI ID: MGI:6273535
• Synonyms: Dnase1l3^LacZ
• Gene: Dnase1l3 Location: Chr14:14475014-14504586 bp, + strand Genetic Position: Chr14, 4.67 cM, cytoband A1
• Alliance: Dnase1l3^tm1Tac page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:234651
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• A lacZ reporter gene and a neomycin selection cassette replaced a portion of the gene. (J:234651)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dnase1l3 Mutation: 26 strains or lines available

References

• Original: J:234651 Sisirak V, et al., Digestion of Chromatin in Apoptotic Cell Microparticles Prevents Autoimmunity. Cell. 2016 Jun 30;166(1):88-101
• All: 6 reference(s)