Il36a^em1Imjc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Il36a^em1Imjc
• Name: interleukin 36A; endonuclease-mediated mutation 1, Tadashi Okamura
• MGI ID: MGI:6273534
• Gene: Il36a Location: Chr2:24105429-24115713 bp, + strand Genetic Position: Chr2, 16.26 cM, cytoband A3
• Alliance: Il36a^em1Imjc page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Parts of exon 2 and exon 3 including the ATG start site were deleted by CRISPR/cas9 mediated recombination. (J:268849)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Il36a Mutation: 10 strains or lines available

References

• Original: J:268849 Ichii O, et al., IL-36alpha Regulates Tubulointerstitial Inflammation in the Mouse Kidney. Front Immunol. 2017;8:1346
• All: 1 reference(s)