Chrna10^tm2.1Bjmy
Targeted Allele Detail

Summary

• Symbol: Chrna10^tm2.1Bjmy
• Name: cholinergic receptor, nicotinic, alpha polypeptide 10; targeted mutation 2.1, Barbara J Morley
• MGI ID: MGI:6273515
• Synonyms: Chrna10^tm2.1Geno
• Gene: Chrna10 Location: Chr7:101760473-101766035 bp, - strand Genetic Position: Chr7, 54.71 cM
• Alliance: Chrna10^tm2.1Bjmy page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:268887
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129Sv/Pas

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 1 and an FRT flanked neo cassette and loxP site were inserted downstream of exon 3 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:101977, J:268887)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Chrna10 Mutation: 18 strains or lines available

References

• Original: J:268887 Morley BJ, et al., Generation and Characterization of alpha9 and alpha10 Nicotinic Acetylcholine Receptor Subunit Knockout Mice on a C57BL/6J Background. Front Neurosci. 2017;11:516
• All: 2 reference(s)