Mitf^em2Gane
Endonuclease-mediated Allele Detail

Summary

• Symbol: Mitf^em2Gane
• Name: melanogenesis associated transcription factor; endonuclease-mediated mutation 2, Anand Ganesan
• MGI ID: MGI:6273203
• Gene: Mitf Location: Chr6:97784013-97998310 bp, + strand Genetic Position: Chr6, 45.05 cM
• Alliance: Mitf^em2Gane page

Mutation origin

• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Endonuclease-mediated (Modified isoform(s))
• Mutation: Intragenic deletion
• CRISPR-targeting deleted 18 bp resulting in the loss of the M isoform. (J:284200)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mitf Mutation: 74 strains or lines available

References

• Original: J:284200 Flesher JL, et al., Delineating the role of MITF isoforms in pigmentation and tissue homeostasis. Pigment Cell Melanoma Res. 2020;33(2):279-292
• All: 1 reference(s)