Mroh2b^em1(IMPC)J
Endonuclease-mediated Allele Detail

Summary

• Symbol: Mroh2b^em1(IMPC)J
• Name: maestro heat-like repeat family member 2B; endonuclease-mediated mutation 1, Jackson
• MGI ID: MGI:6273151
• Gene: Mroh2b Location: Chr15:4928219-4991687 bp, + strand Genetic Position: Chr15, 1.98 cM, cytoband A1
• Alliance: Mroh2b^em1(IMPC)J page
• IMPC: Mroh2b gene page

Mutation origin

• Strain of Origin: C57BL/6NJ
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at The Jackson Laboratory using Cas9 and guides with spacer sequences AGTGGTTTCCTTCAGACCCA and GCTTTAATAGCTTAAAGTAT that targeted exon(s) ENSMUSE00000124014.4 ENSMUSE00000124016.4. This resulted in deletion(s) of 1100 bp (location: Chr15:4934287-4935386; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Mroh2b Mutation: 103 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 3 reference(s)