Eif4g3^tm1.2Hand
Targeted Allele Detail

Summary

• Symbol: Eif4g3^tm1.2Hand
• Name: eukaryotic translation initiation factor 4 gamma, 3; targeted mutation 1.1, Mary Ann Handel
• MGI ID: MGI:6272320
• Gene: Eif4g3 Location: Chr4:137719090-137934397 bp, + strand Genetic Position: Chr4, 70.02 cM
• Alliance: Eif4g3^tm1.2Hand page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:256976
• Parent Cell Line: JM8A3 (ES Cell)
• Strain of Origin: C57BL/6N-A^tm1Brd

Mutation description

• Allele Type: Targeted (Not Specified)
• Mutation: Intragenic deletion
• Mutation details: the loxP-flanked exon 5 was crossed to a cre-deleter strain resulting in an allele that generates protein lacking the conserved N-terminal sequence encoded by exon 5. (J:256976)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Eif4g3 Mutation: 107 strains or lines available

References

• Original: J:256976 Hu J, et al., Nuclear localization of EIF4G3 suggests a role for the XY body in translational regulation during spermatogenesis in mice. Biol Reprod. 2018 Jan 1;98(1):102-114
• All: 1 reference(s)