Map3k8^tm1Lmon
Targeted Allele Detail

Summary

• Symbol: Map3k8^tm1Lmon
• Name: mitogen-activated protein kinase kinase kinase 8; targeted mutation 1, Lluis Montoliu
• MGI ID: MGI:6272273
• Synonyms: Cot/tpl2 KO
• Gene: Map3k8 Location: Chr18:4331325-4352978 bp, - strand Genetic Position: Chr18, 2.73 cM
• Alliance: Map3k8^tm1Lmon page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:166781
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Not Specified
• No molecular details are provided. (J:166781)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Map3k8 Mutation: 44 strains or lines available

References

• Original: J:166781 Soria-Castro I, et al., Cot/tpl2 (MAP3K8) mediates myeloperoxidase activity and hypernociception following peripheral inflammation. J Biol Chem. 2010 Oct 29;285(44):33805-15
• All: 8 reference(s)