Gpr151^em1Yjg
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gpr151^em1Yjg
• Name: G protein-coupled receptor 151; endonuclease-mediated mutation 1, Yong-Jing Gao
• MGI ID: MGI:6268773
• Synonyms: GPR151^-
• Gene: Gpr151 Location: Chr18:42710946-42712717 bp, - strand Genetic Position: Chr18, 22.71 cM
• Alliance: Gpr151^em1Yjg page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Exon 1 was targeted using a pair of TALEN mRNAs coding for forward and reverse TALEs joined to FokI endonuclease. The resulting mutation is the deletion of seven basepairs (ATGGCCG). (J:267550)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gpr151 Mutation: 19 strains or lines available

References

• Original: J:267550 Jiang BC, et al., Demethylation of G-Protein-Coupled Receptor 151 Promoter Facilitates the Binding of Kruppel-Like Factor 5 and Enhances Neuropathic Pain after Nerve Injury in Mice. J Neurosci. 2018 Dec 5;38(49):10535-10551
• All: 1 reference(s)