Gt(ROSA)26Sortm1(CAG-Tpp1)Plob
Targeted Allele Detail
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Symbol: |
Gt(ROSA)26Sortm1(CAG-Tpp1)Plob |
Name: |
gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Peter Lobel and David Sleat |
MGI ID: |
MGI:6259153 |
Synonyms: |
TgLSL-Tpp1 |
Gene: |
Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
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Alliance: |
Gt(ROSA)26Sortm1(CAG-Tpp1)Plob page
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Allele Type: |
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Targeted (Conditional ready, Inserted expressed sequence) |
Mutation: |
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Insertion
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Gt(ROSA)26Sortm1(CAG-Tpp1)Plob expresses
1 gene
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Mutation details: A construct containing a loxP-flanked neo and STOP cassette was inserted between the chicken actin promoter (CAG) and the murine Tpp1 cDNA was integrated into the ROSA26 locus by homologous recombination. This creates a conditional-ready allele from which the gene will only be expressed after cre-mediated recombination of the STOP cassette.
(J:259577)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Gt(ROSA)26Sor Mutation: |
945 strains or lines available
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Original: |
J:259577 Nemtsova Y, et al., Inducible transgenic expression of tripeptidyl peptidase 1 in a mouse model of late-infantile neuronal ceroid lipofuscinosis. PLoS One. 2018;13(2):e0192286 |
All: |
1 reference(s) |
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